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2.45am GMT

With that I’ll be handing over to my colleague Josh Taylor. Thanks for reading and stay with us.

2.37am GMT

A great explanation of how an mRNA vaccine works from Senanayake: “I’m a simple-minded fellow. The way I think about this is if you think of the ingredients of a cake – butter, sugar, eggs, milk – that’s your mRNA vaccine. It’s delivered directly into the body cells and the cell – the kitchen machinery in the cell – makes a spike protein and that releases it into the body system.

“The AstraZeneca vaccine [which is not an mRNA vaccine], is very similar except you get a deliveryman, the adenovirus, holding onto those raw ingredients. The delivery man goes in the cell and gets killed. [Pause for laughter]. The spike protein is made by the cell and released into the system.”

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Source: The Guardian